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If this effect could be proven out in humans, it could be helpful for obesity and type II diabetes [16]. Also in mice, cardarine was linked to increased development of muscle fibers [17]. Cardarine was initially under investigation for preventing obesity by enhancing insulin sensitivity, increasing fat-burning, and reducing blood lipids, testolone half life. Cardarine activates the PPAR- pathway and does not work on the androgen receptors in the muscle and bone tissues directly., testolone half life.